Stanford Society of
Physician Scholars  

Boris Heifets MD, PhD

Resident, Stanford Department of Anesthesiology

Undergraduate: Yale University
Medical School: Albert Einstein College of Medicine
Graduate School: Albert Einstein/Sue Golding Graduate division

Current research focus: Applications of what we know about synaptic plasticity and molecular pharmacology both to the surgical treatment of neurological disorders (e.g. Parkinson’s Disease), as well as to the prevention of neurological complications of surgery (e.g. Postoperative Cognitive Disorder). Using recently developed methods allowing for highly targeted in vivo neural stimulation and recording, and animal models of these disorders we have the ultimate goal of developing therapies for human use.

Opportunities to work with Dr. Boris Heifets: I welcome both medical students and undergraduate students to work with me on my research and clinical service.



Heifets BD, Castillo PE. Endocannabinoid Signaling and Long-term Synaptic Plasticity. Annu Rev Physiol. 2009. 71:283-306.

Heifets BD, Chevaleyre V, Castillo PE. Interneuron activity controls endocannabinoid mediated presynaptic plasticity through calcineurin. Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10250-5.

*Chevaleyre V, *Heifets BD, Kaeser PS, Sudhof TC, Castillo PE. Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1alpha. Neuron. 2007 Jun 7;54(5):801-12. (*contributed equally)

Gold SJ, Heifets BD, Pudiak CM, Potts BW, Nestler EJ. Regulation of regulators of G protein signaling mRNA expression in rat brain by acute and chronic electroconvulsive seizures. J Neurochem. 2002. Aug;82(4):828-38.

Woodruff-Pak DS, Green JT, Pak JT, Heifets B, Pak MH. The effect of scopolamine in older rabbits tested in the 750 ms delay eyeblink classical conditioning procedure. Integr Physiol Behav Sci. 2002 Apr-Jun;37(2):103-13.

Pak J, Green J, Heifets B, Pak M, Woodruff-Pak D. Nefiracetam ameliorates associative learning impairment in the scopolamine-injected older rabbit. Med Sci Monit. 2002 Apr;8(4):BR105-12.

Baggott M, Heifets B, Jones RT, Mendelson J, Sferios E, Zehnder J. Chemical analysis of ecstasy pills. JAMA. 2000 Nov 1;284(17):2190.

Witkin JM, Gasior M, Heifets B, Tortella FC. Anticonvulsant efficacy of N-methyl-D-aspartate antagonists against convulsions induced by cocaine. J Pharmacol Exp Ther. 1999 May;289(2):703-11.

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